- Any acute onset of hypotension or bronchospasm or upper airway obstruction where anaphylaxis is considered possible, even if typical skin features are not present OR
- Any acute onset illness with typical skin features (urticarial rash or erythema/flushing, and/or angioedema), PLUS involvement of respiratory and/or cardiovascular and/or persistent severe gastrointestinal symptoms”, (ASCIA, 2010).
If allergic reaction is deemed to involve more than two body systems, and it is therefore no
longer localised, anaphylaxis should be considered.
Read the complete article; Anaphylaxis in the Medical Library > Pathophysiology.