UNCONTROLLED WHEN PRINTED
 Introduction
  • A naturally occurring sympathomimetic agent
  • Causes peripheral vasoconstriction
  • Stimulation of cardiac conduction system causes increased contractions
  • Causes bronchial smooth muscle relaxation the helps alleviate bronchospasm, wheezing and dyspnoea
  • Alleviates pruritus, urticaria, and angioedema and relieves gastrointestinal and genitourinary symptoms due to relaxant effects on the smooth muscle of the stomach, intestine, uterus, and urinary bladder

Onset:

  • Onset of action is 60 seconds; duration of effect is short and half-life is 5 minutes.
 Indications
 Contraindications
  • There are no absolute contraindications to adrenaline
 Precautions / Notes
  • ALWAYS give adrenaline auto-injector FIRST and then asthma reliever puffer if someone with known asthma and allergy to food, insects or medication has sudden breathing difficulty (e.g. wheeze, persistent cough or hoarse voice), even if there are no skin symptoms
  • Patient’s own injector may be used
  • Do not walk or stand patient pre or post adrenaline administration - usually a minimum of 1 hour after 1 dose of adrenaline and 4 hours if more than 1 dose of adrenaline given
  • Advise transport to a medical facility due to risk of bi-phasic reactions
 Preparation
Preparation
 Management
 Weight-based Calculations
 
Clear
 kg 
Mode: 
Weight: 
Cefazolin for fractures/prophylaxis
Presentation: /mL
Calculated dose:  in

  • Position patient supine, or in a left lateral / recovery position if patient unconscious or pregnant
  • Prepare adrenaline auto-injector as per device available (Anapen® or EpiPen®)

Children 7.5-20kg (aged around one to five years):

  • EpiPen® Jr (150 MICROg) or
  • Anapen® 150 (Jr) (150 MICROg)

Children over 20kg and adults

  • EpiPen® (300 MICROg) or
  • Anapen® 300 (300 MICROg)

Children and adults over 50kg 

  • Anapen® 500 (500 MICROg) or
  • Anapen® 300 (300 MICROg) or
  • EpiPen® (300 MICROg)
 Special Considerations
  • Tachycardia, palpitations
  • Arrhythmias
  • Hypertension (may be marked)
  • Tremor
  • Anxiety
Presentation
  • EpiPen® (yellow label): 300 MICROg
  • EpiPen Jnr® (green label): 150 MICROg
  • Anapen® Jr: 150 MICROg
  • Anapen® 300: 300 MICROg
  • Anapen® 500: 500 MICROg

EpiPen-devices-nov-2021

Anapen-devices-nov2021

Settings
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References
References

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