UNCONTROLLED WHEN PRINTED
Introduction
- A naturally occurring sympathomimetic agent
- Causes peripheral vasoconstriction
- Stimulation of cardiac conduction system causes increased contractions
- Causes bronchodilation and dilation of blood vessels in muscles
Onset:
- Onset 30-90 seconds, lasting up to 20 min.
Indications
- Anaphylaxis / Severe Allergic Reaction as per CPG
Contraindications
- There are no absolute contraindications for adrenaline in these situations.
Precautions / Notes
- ALWAYS give EpiPen® FIRST and then asthma reliever puffer if someone with known asthma and allergy to food, insects or medication has sudden breathing difficulty (e.g. wheeze, persistent cough or hoarse voice), even if there are no skin symptoms
- Patient’s own injector may be used
- Do not walk patient pre/post EpiPen administration
- Advise transport to a medical facility due to risk of bi-phasic reactions
Management
- Position patient supine, or in recovery position if unconscious.
- Dose: Prepare EpiPen and give - lateral mid-thigh.
Adult/Paediatric ≥ 20kg/≥5yo
- 0.3mg repeat every 5 min as clinically indicated
Infant/Paediatric <20kg/<5yo
- 0.15mg repeat every 5 min as clinically indicated
Special Considerations
- Tachycardia, arrhythmias
- Increase in blood pressure (may be marked)
- Tremor, anxiety
References
References
Presentation
- EpiPen® (yellow label): 0.3mg
- EpiPen Jnr® (green label): 0.15mg
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