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Introduction
Aspirin has the following pharmacological actions:
- Analgesic
- Antipyretic
- Anti-inflammatory
- Anti-platelet aggregation agent
Reduces mortality significantly in Acute Myocardial Infarction by minimising platelet aggregation and thrombus formation in order to retard the progression of coronary artery thrombosis.
Indications
- Chest pain / discomfort of presumed cardiac origin.
Contraindications
- Known hypersensitivity to aspirin / salicylates.
- Children < 12 years of age.
Precautions / Notes
- Actively bleeding peptic ulcers.
- Suspected AAA.
- Aspirin / salicylate-sensitive asthmatics
Management
- 300mg oral administration, preferably chewed.
- Administered even if patient has taken aspirin that day or on anticoagulants.
Special Considerations
- Heart burn, nausea, GI bleeding.
- Increased bleeding time.
- Anaphylactic reaction (some patients, especially asthmatics) exhibit notable sensitivity to aspirin, which may provoke various hypersensitivity / allergic reactions)
References
References
Presentation
300mg white tablet
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