• Paracetamol is a p-aminophenol derivative that exhibits analgesic and antipyretic activity.
  • Delayed onset of action with peak effect via oral route achieved in ≥ 30 minutes.

Pharmacology Review

  • Mild to moderate pain
    • For example, headache, sprain/strain, toothache, etc.
    • As a component of a multimodal analgesic regime.
  • Known hypersensitivity to Paracetamol.
  • Do not give if patient has had Paracetamol in the preceding 4 hours.
  • Cannot exceed the maximum allowed single dose or exceed the maximum allowed paracetamol daily dose (24hrs).
Critical Care

IV only:

  • Children < 12 months
 Precautions / Notes
  • There is no evidence that fever itself worsens the course of an illness. The primary goal should be to improve overall comfort [1]
  • SJA do not support the use of paracetamol in infants < 6 months.
  • 100mg/mL suspension bottle (20 mL) Paracetamol suspension bottle is single patient use only.
  • Only used enteral syringe/dropper with suspension [2]
 Weight-based Calculations
Oral Paracetamol Suspension
Presentation: 2000mg:20mL
Calculated dose:  in


  • 500mg tablet; oral administration of 500-1000mg (1-2 tablets)
  • Maximum single dose 1000mg
  • Maximum dose not to exceed 4000mg over a 24-hour period

Paediatric (6 months – 12 years old; oral suspension only):

  • 15mg/kg
  • Maximum single dose 1000mg
  • Repeat every 4 to 6 hours
  • Maximum daily dose is 60mg/kg (in divided doses of 15mg/kg over a 24-hour period) and is not to exceed 4000mg over a 24-hour period.
Critical Care


  • 1g IV


  • 15mg/kg
 Special Considerations
  • Nil known at therapeutic doses.
  • 500mg white tablets
  • 100mg/mL (2000mg/20ml) suspension
Critical Care
  • 10mg/mL (1000mg/100mL) infusion


Panadol Suspension Box

Panadol Suspension

Current mode:
Extended Care:
Colour assist:

Janice E. Sullivan, H. C. (n.d.). Clinical Report - Fever and Antipyretic use in Children. The American Academy of Pediatrics.

Document Control

Clinical Services

Responsible Manager
Head of Clinical Services


Issue Date

Expiry Date

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