UNCONTROLLED WHEN PRINTED
Introduction
  • A naturally occurring anticoagulant which inhibits the clotting of blood by enhancing the rate at which antithrombin III neutralises thrombin and activated factor X (Xa).
  • Onset of action is immediate following IV administration.

Pharmacology Review

Indications
  • Patients with STEMI going directly to Cardiac Catheterisation Laboratory as per receiving hospital 12-lead ECG interpretation.
Contraindications
  • Hypersensitivity to Heparin
  • Presence of known haemorrhagic states
Precautions / Notes
  • Haemorrhagic risks in case of possible trauma.
Management
  • IV only: 5000IU / 5ml bolus dose flushed with NaCl 0.9%.
Special Considerations
  • Haemorrhage

References
References
Presentation
Ampoule of 5,000 international units (IU) in 5mL
Heparin (2)
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Responsible Manager
Head of Clinical Services

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