- Paracetamol is a p-aminophenol derivative that exhibits analgesic and antipyretic activity.
- Delayed onset of action with peak effect via oral route achieved in ≥ 30 minutes.
- Mild to moderate pain
- For example, headache, sprain/strain, toothache, etc.
- As a component of a multimodal analgesic regime.
- Known hypersensitivity to Paracetamol.
- Do not give if patient has had Paracetamol in the preceding 4 hours.
- Cannot exceed the maximum allowed single dose or exceed the maximum allowed paracetamol daily dose (24hrs).
IV only:
- Children < 12 months
- There is no evidence that fever itself worsens the course of an illness. The primary goal should be to improve overall comfort [1]
- SJA do not support the use of paracetamol in infants < 6 months.
- 100mg/mL suspension bottle (20 mL) Paracetamol suspension bottle is single patient use only.
- Only used enteral syringe/dropper with suspension [2]
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Oral Paracetamol Suspension
Adult:
- 500mg tablet; oral administration of 500-1000mg (1-2 tablets)
- Maximum single dose 1000mg
- Maximum dose not to exceed 4000mg over a 24-hour period
Paediatric (6 months – 12 years old; oral suspension only):
- 15mg/kg
- Maximum single dose 1000mg
- Repeat every 4 to 6 hours
- Maximum daily dose is 60mg/kg (in divided doses of 15mg/kg over a 24-hour period) and is not to exceed 4000mg over a 24-hour period.
Adult:
- 1g IV
Paediatric:
- 15mg/kg
- Nil known at therapeutic doses.
- 500mg white tablets
- 100mg/mL (2000mg/20ml) suspension
- 10mg/mL (1000mg/100mL) infusion
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