- A narcotic analgesic acting on CNS by binding with opioid receptors
- Also combines to cause respiratory depression, vasodilation, decreases gag reflex and slows AV node conduction
Onset & duration:
- IM: Onset 5-10 minutes; Peak 20-30 minutes; Duration 1-2 hours
- IV/IO: Onset 2-5 minutes; Peak 20 minutes; Duration 1-2 hours
- Severe pain
- Sedation to maintain intubation
- Hypersensitivity to morphine or other opioids
- Renal impairment / failure
- Late second stage of labour
- Reduce doses for elderly, frail and low body weight patients
- Hypotension, shock
- Patient with respiratory depression, severe COPD
- Respiratory tract burns
- Patients on monoamine oxidase inhibitor
- Patients with severe hepatic impairment
- For IV injection, dilute 15mg/1mL with 14mL water for injection to make 15mg/15mL (1mg/mL), and inject slowly over 4-5 minutes.
| kg | ||
| Mode: | ||
| Weight: | ||
IM Morphine for analgesia
IV Morphine for analgesia
IV Morphine for sedation to maintain intubation
Commence at 5mg/hr, titrate to effect.
Adult < 70 years:
- IM: 5 – 10 mg
- IV/IO: 2.5 – 5 mg
- Repeat every 5 minutes. as needed, titrating to response
Adult > 70 years:
- IM: 2 – 5 mg
- IV/IO: 0.5 – 2.5 mg
- Repeat every 5 minutes. as needed, titrating to response
Paediatric > 1 year:
- IM: 0.1 – 0.2 mg/kg, maximum dose 5 mg
- IV/IO: 0.05 – 0.1 mg/kg, maximum bolus dose 2.5mg. Repeat dose every 5 minutes as needed, titrating to effect
- Maximum dose 0.4 mg/kg
- Do not exceed 20 mg
Adult:
- 1 – 20 mg/hr IV/IO; consider co-administration with midazolam
- Commence at 5 mg/Hr titrate to effect
Paediatric > 1 year:
- 0.01 – 0.04 mg/kg/hr IV/IO; consider co-administration with Midazolam.
- Not to exceed adult doses above
- Bradycardia
- Hypotension
- Drowsiness
- Nausea and/or vomiting
- Pinpoint pupils
- Respiratory depression
- Constipation
15 mg in 1 mL ampoule
| Settings | |
|---|---|
| Current mode: | |
| Extended Care: | |
| Colour assist: | |
Discarding unused medication must be witnessed and countersigned by attendant and credible witness.
Document Control
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