UNCONTROLLED WHEN PRINTED
 Introduction
  • A sterile isotonic crystalloid solution

Pharmacology Review

 Indications
  • Fluid replacement (volume expansion) for the treatment of shock, fluid loss, and cardiac arrest.
 Contraindications
  • Severe Pulmonary Oedema
 Precautions / Notes
  • Adult patients with penetrating trauma, ectopic pregnancy or aortic aneurysm with hypotension and signs of impaired organ perfusion may benefit from permissive hypotension (systolic blood pressure of 70mmHg)
  • Fluid Therapy for shock, DKA & Hyperosmolar Hyperglycaemic State: Initial fluid therapy is directed toward expansion of the intravascular, interstitial, and intercellular volume, all of which are reduced in hyperglycaemic crises and restoration of renal perfusion.
 Preparation
Preparation
 Management
 Weight-based Calculations
 
Clear
 kg 
Mode: 
Weight: 
IV Saline for Cardiac Arrest
Calculated dose: 
IV Saline for Post ROSC
Calculated dose: 
Subsequent dose: 
IV Saline for shock, DKA, HHS
Calculated dose:  over 5-10mins
IV Saline for burns
Total Burn Surface Area (TBSA, %)
Fluid administration (mL):  
50% (mL) of total amount over the first 8 hours
mL ( drops) per minute
mL per hour
50% (mL) of total amount over next 16 hours
IV Saline for haemorrhage
Calculated dose:  (4x repeat to a maximum of 1L)

KVO
  • 20 drops per minute (20 drops = 1ml)
Fluid Therapy for shock, DKA & Hyperosmolar Hyperglycaemic State
Adult:
  • 250ml boluses to a maximum total of 2000ml
  • Small adult/elderly 250ml boluses up to maximum total of 1000ml

Paediatric:

  • 10ml/kg over 5-10 minutes. Repeat once only
Haemorrhage

Adult:

  • Infuse 250ml boluses maximum total 2000ml with reassessment between each infusion

Paediatric:

  • Hypotensive paediatric patients should receive IV fluids; 10ml/kg (max. 250ml bolus) reassessment between each bolus (4x infusions maximum) to a total infusion not exceeding 1000ml
Cardiac Arrest

Adult / Paediatric:

  • 20ml/kg bolus as a reversible cause of hypovolaemia

Newborn:

  • 10ml/kg as a reversible cause of hypovolaemia
Post ROSC
  • Manage hypotension in Post-ROSC patients if BP is slow to rise:
    • The patient is considered hypotensive if Systolic BP is:
      • Adult: < 100mmHg
      • Paediatric: < 80mmHg

Adult:

  • 250ml boluses to a maximum total of 500ml with reassessment between each infusion

Paediatric:

  • 10ml/kg, repeat once only with reassessment between each infusion (bolus max. 250ml)
Burns

Apply modified Parkland Formula to patients that meet the following criteria:

Adults:

  • > 15% TBSA

Paediatrics:

  • ≥ 18 months and > 10% TBSA OR
  • < 18 months and > 8% TBSA

Modified Parkland Formula:

  • 2ml x %TBSA x weight of patient
  • 50% of total amount over first 8 hours
  • 50% of total amount over next 16 hours

Parkland Calculator

An online calculator to assist in determining fluid administration for burns.

Parkland Calculator

Critical Care & Paramedic – Special Operations
  • Consider MEQU Fluid & Blood Warmer for intravenous fluid replacement in:
    • Paediatric patients
    • Burns patients
    • Patients with hypothermia 
Crush Injury
  • 20mL/kg bolus doses titrated to effect
  • Subsequent dosages of 20mL/kg/hr (Maximum total dose 60mL/kg i.e. 2 hours entrapment)
  • Consult ASMA for further advice
 Special Considerations
  • Hypervolemia
Presentation
  • Normal saline (NaCl 0.9%) in 1000 ml soft plastic bag
  • Normal saline (NaCl 0.9%) in 250 ml soft plastic bag
  • 10 ml plastic vial
  • Normal saline (NaCl 0.9%) sterile pre-filled 5 ml flush syringe
BD 5ml POSI flush
Saline-250
10ml-saline
1000ml-saline
Settings
Current mode:
Extended Care:
Colour assist:

References
Kitabchi, A.E., Umpierrez, G.E., Miles, J.M. and Fisher, J.N. (2009). Hyperglycemic Crises in Adult Patients With Diabetes. Diabetes Care, [online] 32(7), pp.1335–1343. doi: https://doi.org/10.2337/dc09-9032 .

Document Control


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Clinical Services

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